DelveInsight’s, “Retinitis Pigmentosa Pipeline Insight 2023” report provides comprehensive insights about 45+ companies and 45+ pipeline drugs in the Retinitis Pigmentosa pipeline landscape. It covers the Retinitis Pigmentosa pipeline drug profiles, including Retinitis Pigmentosa clinical trials and nonclinical stage products. It also covers the Retinitis Pigmentosa therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Key Takeaways from the Retinitis Pigmentosa Pipeline Report
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Retinitis Pigmentosa Overview
Retinitis pigmentosa (RP) is an umbrella term for a group of hereditary progressive retinal disorders that cause progressive degeneration of the retina. The disease is inherited as autosomal recessive, autosomal dominant or X-linked recessive traits. Signs of retinitis pigmentosa usually appear during childhood or adolescence.
Retinitis Pigmentosa Emerging Drugs
BIIB-112 (formerly called NSR-RPGR) consists of a standard AAV8 vector carrying a codon optimized RPGR gene. BIIB112 is in phase II clinical studies for X-linked retinitis pigmentosa treatment. In September 2018, NSR-RPGR was granted orphan drug designation for the treatment of inherited retinal dystrophies due to defects in the RPGR gene from the U.S. Food and Drug Administration.
QR 1123 (formerly ISIS RHO 2.5Rx) is an antisense oligonucleotide, designed to specifically target the mutant P23H messenger ribonucleic acid (mRNA) in order to reduce the expression of the P23H protein selectively, while preserving expression of the wild type (WT) rhodopsin (RHO) protein. The therapy is currently in Phase II clinical evaluation for the treatment of Retinitis Pigmentosa. In November 2019, ProQR Therapeutics announced that it received Orphan Drug designation (ODD) from the Food and Drug Administration (FDA) for QR-1123. QR-1123 was in-licensed from Ionis Pharmaceuticals in 2018. QR-1123 has also received Fast Track designation from the FDA.
For further information, refer to the detailed Retinitis Pigmentosa Drugs Launch, Retinitis Pigmentosa Developmental Activities, and Retinitis Pigmentosa News, click here for Retinitis Pigmentosa Ongoing Clinical Trial Analysis
Retinitis Pigmentosa Pipeline Therapeutics Assessment
There are approx. 45+ key companies which are developing the therapies for Retinitis Pigmentosa. The companies which have their Retinitis Pigmentosa drug candidates in the most advanced stage, i.e. Phase II include, Biogen.
Retinitis Pigmentosa Segmentation: Phases
Find out more about the Retinitis Pigmentosa Pipeline Segmentation, Therapeutics Assessment, and Retinitis Pigmentosa Emerging Drugs @ Retinitis Pigmentosa Treatment Landscape
Table of Content
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